A Sequence-Based Analysis of the Pointer Distribution of Ciliate (bibtex)
by Alhazov, Artiom, Petre, Ion and Verlan, Sergey
Abstract:
It has long been known that the lengths of some of the pointers in the micronuclear ciliate genes are too short to allow for the unambiguous recognition of their coding and noncoding blocks. Many of these pointers have multiple occurrences along the gene, allowing for a very high number of possible divisions into coding and noncoding blocks. We investigate in this paper the pointer distribution of all currently sequenced micronuclear ciliate genes with the goal of identifying what distinguishes the real gene structure among all possible coding/noncoding divisions. We find a surprisingly sharp criterium in the total AT percentage of the IESs of each such division: the real gene has, in most cases, the maximum such percentage among all possible combinations.
Reference:
A Sequence-Based Analysis of the Pointer Distribution of Ciliate (Alhazov, Artiom, Petre, Ion and Verlan, Sergey), Technical report 902, , 2008.
Bibtex Entry:
@TechReport{t193,
author   = {Alhazov, Artiom AND Petre, Ion AND Verlan, Sergey},
title    = {A Sequence-Based Analysis of the Pointer Distribution of Ciliate},
year     = {2008},
number   = {902},
abstract = {It has long been known that the lengths of some of the pointers in the micronuclear ciliate genes are too short to allow for the unambiguous recognition of their coding and noncoding blocks. Many of these pointers have multiple occurrences along the gene, allowing for a very high number of possible divisions into coding and noncoding blocks. We investigate in this paper the pointer distribution of all currently sequenced micronuclear ciliate genes with the goal of identifying what distinguishes the real gene structure among all possible coding/noncoding divisions. We find a surprisingly sharp criterium in the total AT percentage of the IESs of each such division: the real gene has, in most cases, the maximum such percentage among all possible combinations.},
file     = {APV2008a.pdf:pdfs/APV2008a.pdf:PDF},
keywords = {Ciliates, pointers, sequence analysis, pointer distribution},
}